GLP-1 therapies (e.g., Mounjaro, Zepbound) are driving breakthrough outcomes in obesity, type 2 diabetes, and cardiometabolic disease. However, their high cost, limited access, and uneven prescribing threaten to deepen health inequities and strain payer budgets.

As shortages end and lower-cost compounded options vanish, only those with high incomes or generous benefits can afford access, leaving vulnerable populations behind.

Asian, Black, and Hispanic patients are significantly less likely to receive GLP-1s even when clinically indicated for diabetes.

More than 42,000 U.S. deaths could be prevented annually through broader access (PNAS, 2023).

“Costly innovation without equitable access is not a sustainable model.”

Avalon

Avalon addresses these challenges by helping payers shift from subjective or BMI-only criteria to lab-informed, data-driven eligibility that aligns GLP-1 access with medical necessity.